Pharmaceutics

This page contains key pharmaceutical news on drug recalls, FDA clearance, safety communications and research. In cardiology, key pharmaceutic agents include antiplatelet therapies, anticoagulants, hypertension drugs, and drugs for heart failure and arrhythmias.   

FDA posts guidance on managing risk of drug shortages

The Food & Drug Administration has drafted guidelines to help U.S. healthcare better prepare for and respond to events associated with these situations.

The FDFA has cleared tirzepatide (Mounjaro) from Eli Lilly for the treatment of diabetes.

FDA approves tirzepatide, Eli Lilly’s new type 2 diabetes drug, and the company shares an estimated price

The medication, sold under the name Mounjaro, will be available in six different doses and come in an auto-injector pen.

FDA asks drug makers to address shortages

Drug shortages have been impacted by COVID-19, with 95% of doctors believing the pandemic exposed weaknesses in the medicine supply chain.

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New bleeding stroke guidelines highlight several common treatments that may be ineffective

The updated document, developed by the American Heart Association and American Stroke Association, also emphasizes the potential benefits of caregiver training and MR imaging. 

Flu shots lower CVD risk, new meta-analysis confirms

The study's authors tracked data from six different randomized controlled trials, including a large study from 2021 that focused on myocardial infarction patients.

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Combining certain BP medications with NSAIDs linked to kidney damage—acetaminophen seen as a safer option

A team of researchers used computer science and mathematics to study the "triple whammy" of diuretics, RAS inhibitors and NSAIDs.

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How the science behind COVID-19 vaccines could transform care for heart attack patients

A technique seen in the Pfizer-BioNTech and Moderna COVID-19 vaccines may be able to help heart cells repair themselves, according to new research out of the Netherlands. 

mavacamten

FDA approves mavacamten for obstructive hypertrophic cardiomyopathy

The FDA’s approval was based on data from the EXPLORER-HCM trial, which showed that mavacamten was superior to a placebo for treating obstructive HCM and associated with no significant long-term, treatment-related adverse events.