Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Empagliflozin provides consistent benefits for HFpEF patients

Researchers took a fresh look at data from the EMPEROR-Preserved trial, sharing their findings in Circulation.

Stem cell therapy for heart failure lowers risk of adverse outcomes

“Cell therapy has the potential to change how we treat heart failure,” one researcher said.

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New risk calculator detects TEER patients who may need to be readmitted for HF

Once the tool's performance is properly validated, it could help clinicians deliver better patient care and result in significant cost savings for health systems.

Some cancer immunotherapies may increase the risk of myocarditis

The study's authors tracked data from facilities in 11 different countries, examining imaging findings from patients with ICI-related myocarditis. 

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Sacubitril/valsartan no better than valsartan alone for advanced heart failure

"Every clinical outcome that we measured favored treatment with valsartan alone," one researcher said. 

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Using pulmonary artery pressure monitoring to manage obese HF patients leads to strong outcomes

Researchers examined data from the CardioMEMS Post Approval Study, sharing their findings in JACC: Heart Failure

Diabetes with cardiomyopathy associated with heightened heart failure risk

At this time, however, clinicians lack an intervention that specifically targets this combination of complications. 

Scenes from the pandemic: Telehealth a perfect fit for treating heart failure

One large health system actually treated more heart failure patients during the pandemic than it had in previous years.