Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

TricValve Transcatheter Bicaval Valves System Cleveland Clinic

Interventional cardiologists complete first heart procedure of its kind in North America

While the system used during the procedure has not yet gained full FDA approval, this patient was treated under a compassionate-use clearance from the agency.

Women who experience infertility may face higher heart failure risk

Researchers examined the health outcomes of 38,528 postmenopausal women—14% of whom had a history of infertility—over a 15-year period. 

The American College of Cardiology (ACC) annual meeting is the premier source for the latest cardiac science. #ACC22

Links to the ACC.22 late-breaking clinical trials

Learn more about the late-breaking studies presented at ACC.22 in Washington, D.C. 

Nurses caring for a COVID-19 patient in the COVID unit at Banner University Medical Center in Phoenix.

An updated look at what cardiologists know about heart damage among COVID-19 patients

An international analysis published in Circulation and a new scientific statement from the American Heart Association both explore the latest data on heart complications associated with COVID-19. 

Researchers share first human data on new interventional shunt procedure for HFpEF

The first-in-man study, completed by a team of cardiologists in China, included 10 patients presenting with HFpEF. 

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European Society of Cardiology publishes new genetic testing guidelines for heart conditions

The new international consensus document gives detailed recommendations on when to offer genetic testing for patients and their family members. 

Steven E. Nissen, MD, discusses his late-breaking clinical trial with panelist Vera Bittner, MD.

Cholesterol medications, flu shots and heart failure: Day 2 at ACC.22

Day 2 of ACC.22 was jam-packed with late-breaking clinical trials. Read our quick rundown of what researchers shared with the public for the very first time. 

Cardiology groups debut new heart failure guidelines ahead of ACC.22

The new recommendations went live just ahead of ACC.22. They can be read in full in the Journal of the American College of Cardiology, Circulation or Journal of Cardiac Failure.