Clinical Research

The variable fluorescence attenuation of blood has been a hindrance to near-infrared fluorescence (NIRF) measurements in cardiovascular imaging. Fortunately, researchers have devised an innovative correction method in which the guidewire (GW) is coated with the fluorescent agent (ICG) and used as a reference standard in each frame, leading to a much higher accuracy. Credit: Rauschendorfer et al., doi 10.1117/1.JBO.28.4.046001

New technique improves accuracy of near-infrared fluorescence imaging

NIRF imaging could help interventional cardiologists personalize care in the cath lab, but a key engineering issue needed to be solved first.

Marielle Scherrer Crosbie and Tomas Neilan explain the STOP-CA trial and how statins can help prevent cardiotoxicity from anthracycline chemo agents.

Statins may help prevent anthracycline cardiotoxicity in chemotherapy

The STOP-CA trial showed that statins can help chemotherapy patients avoid potential side effects related to anthracycline agents. Co-principal investigators Marielle Scherrer-Crosbie, MD, and Tomas Neilan, MD, discussed the details of that trial at ACC.23. 

Thumbnail

Clopidogrel linked to better long-term outcomes than aspirin in PCI patients with and without diabetes

Clopidogrel is especially effective at limiting major adverse cardiovascular events among PCI patients with diabetes, researchers found. 

Imaging required to monitor effects of new Alzheimer's drug could inhibit its uptake

Leqembi can cause amyloid-related imaging abnormalities (ARIA), which must be assessed on imaging.

population level clinical insights

Oracle, John Snow helping FDA turn unstructured clinical notes into population health insights

The FDA-led Sentinel Initiative is tapping Oracle’s life-sciences division, Cerner Enviza, to spearhead development of AI tools for rendering EHR-bound clinical notes as usable pointers for clinicians and researchers.

cardiovascular emergency ambulance

AI could point first responders to ready, willing and able hospitals in real time

People suddenly stricken with a cardiovascular crisis often survive and recover as long as they’re transported ASAP to a hospital that has two attributes: expertise in emergency heart care and capacity to accommodate the incoming episode.

pulsed radiofrequency for sciatica

Pulsed radiofrequency procedure could help patients avoid surgery for sciatica

In PRF procedures, a probe is used to intermittently apply energy directly to the dorsal root ganglia, which is often where pain and neurologic symptoms associated with sciatica originate.  

Thumbnail

Experts identify sex-specific MRI brain signatures associated with obesity

Researchers at the University of California Los Angeles combined multimodal brain MRIs with clinical and personal data from 183 men and women to identify sex-specific brain signatures that could be indicative of what causes a person to develop obesity.