Clinical Research

Key clinical takeaways from ACC.26
Hadley Wilson, MD, a former American College of Cardiology president, spoke to Cardiovascular Business about several studies presented at ACC.26.
PCI before TAVR? In older CAD patients, deferral may be the best approach
Patients with coronary artery disease and severe aortic stenosis often undergo PCI before TAVR. According to new data presented at ACC.26, however, deferring PCI is associated with comparable outcomes as well as a reduced bleeding risk.
Premature menopause linked to substantial long-term heart risks
Starting menopause before the age of 40 could increase a woman's lifetime risk of coronary heart disease by up to 40%.
Cold weather responsible for many more stroke and heart attack deaths than heat
While heat consistently gets more attention in terms of public health messaging, new data show just how dangerous the cold can be.
MRI findings detail how a 'leaky' barrier can damage the brain years after head injuries
New evidence suggests the BBB can remain compromised following a head injury, even years after it first occurred.

Focal pulsed field ablation (PFA) is a safe, effective treatment option for premature ventricular contractions (PVC), according to new data published in Circulation: Arrhythmia and Electrophysiology.[1]

PFA ablation safe, effective for treating premature ventricular contractions

Early data suggest PVC ablation with PFA technology is associated with a high success rate and minimal complications.

Long-term survival after valve-in-valve TAVR similar with self-expanding, balloon-expandable valves

Severe prosthesis-patient mismatch was more common with balloon-expandable valves, but that difference did not appear to impact outcomes.

Heart tissues within one of the Johns Hopkins space launch-ready chambers for study aboard the International Space Station. Photo from Jonathan Tsui.

Space travel disrupts normal rhythm in heart cells

Heart tissue samples that spent 30 days at the International Space Station appear to have been weakened by the low gravity conditions in space. This finding has implications for the heart health of astronauts.

Brain anatomy differs between people with opposing political ideologies

New research indicates that conservatives have larger amygdalas than their more progressive-leaning counterparts.

SAVR associated with several long-term benefits for patients with asymptomatic severe AS

The current evidence suggests early surgery is a better treatment option for asymptomatic severe AS than conservative care, researchers explained.

Harlan Krumholz, MD, SM, editor-in-chief of the Journal of the American College of Cardiology (JACC), and a cardiologist and the Harold H. Hines, Jr. Professor of Medicine at the Yale school Medicine, explains some of the key technology advances he is watching across cardiology.

JACC editor excited by progress during a 'very important moment' for cardiology

Harlan Krumholz, MD, editor-in-chief of the Journal of the American College of Cardiology, explains some of the key technology and treatment trends he has his eyes on.

Nemours Children's Hospital pediatric cardiologists explain lessons learned about cardiac involvement and long-term issues from multisystem inflammatory syndrome in children (MIS-C), a rare but serious disease caused by exposure to the COVID-19 virus. #MIS-C #COVID #coronavirus #SARSCoV2

A key update on how COVID-19 caused dangerous MIS-C inflammation in children

The rise of MIS-C during the COVID-19 pandemic alarmed physicians and patients alike, and the exact cause was unclear. Now, new NIH-funded research appears to provide some answers.

Novel radiotracer could improve the diagnosis of interstitial lung disease

Researchers are hopeful that uptake of the molecular SPECT imaging agent will help providers more ably monitor disease progression.

Clinical Research

Key clinical takeaways from ACC.26

PCI before TAVR? In older CAD patients, deferral may be the best approach

Premature menopause linked to substantial long-term heart risks

Cold weather responsible for many more stroke and heart attack deaths than heat

MRI findings detail how a 'leaky' barrier can damage the brain years after head injuries