Clinical Research

Coronary calcium may predict a patient's risk of dying from noncardiac conditions
Calcium in the coronary arteries is a known cardiac risk factor. However, new data suggest it may actually tell us more about a person's overall health than researchers previously believed.
Prosthesis-patient mismatch after TAVR may not negatively impact quality of life
Researchers warned that “aggressive procedural modifications” should not be necessary during TAVR to mitigate the risk of prosthesis-patient mismatch. This appears to be true for patients receiving both self-expanding and balloon-expandable TAVR valves.
New data question short-term efficacy of anti-amyloid drug
Although the drug can slow the progression of cognitive decline, it may have little impact on damage already done by AD prior to treatment.
MRIs uncover the science behind sports fandom
Sports fans may actually be emotionally dependent on their team’s performance on a neural level, according to functional imaging data.
'Breakthrough' MRI contrast design could make GBCAs safer, more effective
Researchers are hopeful their new approach to developing MRI contrast will "pave the way for safer, smarter imaging in clinical diagnostics."

Focal pulsed field ablation (PFA) is a safe, effective treatment option for premature ventricular contractions (PVC), according to new data published in Circulation: Arrhythmia and Electrophysiology.[1]

PFA ablation safe, effective for treating premature ventricular contractions

Early data suggest PVC ablation with PFA technology is associated with a high success rate and minimal complications.

Long-term survival after valve-in-valve TAVR similar with self-expanding, balloon-expandable valves

Severe prosthesis-patient mismatch was more common with balloon-expandable valves, but that difference did not appear to impact outcomes.

Heart tissues within one of the Johns Hopkins space launch-ready chambers for study aboard the International Space Station. Photo from Jonathan Tsui.

Space travel disrupts normal rhythm in heart cells

Heart tissue samples that spent 30 days at the International Space Station appear to have been weakened by the low gravity conditions in space. This finding has implications for the heart health of astronauts.

Brain anatomy differs between people with opposing political ideologies

New research indicates that conservatives have larger amygdalas than their more progressive-leaning counterparts.

SAVR associated with several long-term benefits for patients with asymptomatic severe AS

The current evidence suggests early surgery is a better treatment option for asymptomatic severe AS than conservative care, researchers explained.

Harlan Krumholz, MD, SM, editor-in-chief of the Journal of the American College of Cardiology (JACC), and a cardiologist and the Harold H. Hines, Jr. Professor of Medicine at the Yale school Medicine, explains some of the key technology advances he is watching across cardiology.

JACC editor excited by progress during a 'very important moment' for cardiology

Harlan Krumholz, MD, editor-in-chief of the Journal of the American College of Cardiology, explains some of the key technology and treatment trends he has his eyes on.

Nemours Children's Hospital pediatric cardiologists explain lessons learned about cardiac involvement and long-term issues from multisystem inflammatory syndrome in children (MIS-C), a rare but serious disease caused by exposure to the COVID-19 virus. #MIS-C #COVID #coronavirus #SARSCoV2

A key update on how COVID-19 caused dangerous MIS-C inflammation in children

The rise of MIS-C during the COVID-19 pandemic alarmed physicians and patients alike, and the exact cause was unclear. Now, new NIH-funded research appears to provide some answers.

Novel radiotracer could improve the diagnosis of interstitial lung disease

Researchers are hopeful that uptake of the molecular SPECT imaging agent will help providers more ably monitor disease progression.

Clinical Research

Coronary calcium may predict a patient's risk of dying from noncardiac conditions

Prosthesis-patient mismatch after TAVR may not negatively impact quality of life

New data question short-term efficacy of anti-amyloid drug

MRIs uncover the science behind sports fandom

'Breakthrough' MRI contrast design could make GBCAs safer, more effective