Clinical Research

Alleviant Medical, a Texas-based medical device company, has received the FDA’s breakthrough device designation and an investigational device exemption (IDE) for its new atrial shunt that treats heart failure without leaving a permanent implant in the body.

FDA sees value in no-implant heart failure device

The new atrial shunt from Alleviant Medical was designed to treat heart failure without leaving a permanent implant behind. The FDA granted the technology its breakthrough device designation and approved additional research. 

Michael Reardon, MD, said monitoring under expansion would have made Acurate Neo2 non-inferior to current TAVR valves in the ACURATE IDE trial.

The primary reason Boston Scientific’s TAVR valve fell short in clinical trial

Michael Reardon, MD, co-principal investigator of the ACURATE IDE trial, discussed updated data on what may have impacted that study's findings.

Sentinel axillary lymph node injected with tattoo ink via ultrasound guidance

Tattoo ink a promising option for localizing sentinel axillary lymph nodes

In some cases, the method even helps to home in on sentinel nodes that may not have been identified during prior biopsy.

Video of Deepak Bhatt explaining details on the TRANSFORM trial using CCTA and AI. #TCT #TCT24 #TCT2024 #AHA24 #AHA2024

New cardiac prevention paradigm explored in TRANSFORM trial using AI and CCTA

Deepak Bhatt, MD, director of the Mount Sinai Fuster Heart Hospital and principal investigator of the TRANSFORM trial, explains an emerging technique for cardiac screening: combining coronary CT angiography with artificial intelligence for plaque analysis to create an approach similar to mammography.

Pigs Pig Stock Photo

Alabama woman first in world to receive 10-gene-edited pig kidney

Towana Looney, 53, is recovering well but still under observation by the NYU Langone doctors who performed the groundbreaking procedure. 

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Repurposed radiotracer lights up treatment-resistant tumors 'like a Christmas tree'

Use of the new tracer could improve outcomes by enabling providers to adjust treatment regimens much earlier than they have been able to previously. 

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For the first time, researchers find a way to spot early signs of pancreatic cancer on routine MRI

Pancreatic cancer is one of the deadliest cancers, with a five-year survival rate of only 44% if caught early, dropping down to 3% if it metastasizes. This is largely due to its ability to elude detection.

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How opioid use disorder affects brain size and function

The CDC estimates that over 6 million people in the U.S. struggle with OUD, and prior research has indicated that only 20% receive treatment for the disorder.