Clinical Research

kid child pediatric MRI imaging

AI predicts pediatric cancer recurrence with impressive accuracy

Researchers have developed a deep learning model that can spot longitudinal changes in patients' brain imaging that could be indicative of cancer recurrence. 

Michael J. Reardon, MD, the Allison Family Distinguished Chair in Cardiovascular Research and a professor of medicine at the DeBakey Heart and Vascular Center, Houston Methodist Hospital, explains the late-breaking five-year results of the Evolut Low-Risk Trial presented at the American College of Cardiology (ACC) 2025 meeting. The data show positive results for the Evolut transcatheter aortic valve replacement (TAVR) system vs. surgical aortic valve replacement (SAVR).

Self-expanding TAVR valves deliver outcomes and durability comparable to surgery after 5 years

Michael Reardon, MD, detailed five-year data out of ACC.25 that found Medtronic's Evolut TAVR platform performs as well as SAVR—and even better in some ways. 

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Underweight TAVR patients face higher mortality risk—obesity makes no significant impact

Reviewing data from more than 6,000 patients, researchers found little evidence of the "obesity paradox" observed elsewhere. Underweight TAVR patients, however, may face some significant long-term risks.

Perfuze Millipede 088 catheter

Perfuze celebrates a ‘major milestone’ for new-look stroke catheter

The Millipede 088 was designed to treat large vessel occlusion stroke patients by “ingesting” the blood clot as opposed to dragging it through the patient’s blood vessels. 

Meril Life Sciences, an India-based medical device company founded in 2006, developed the Myval TAVR valve

Myval TAVR valve non-inferior to Sapien 3 after 1 year—pacemaker implants the biggest difference

India-based Meril Life Sciences has been manufacturing its Myval transcatheter heart valves for years, but the technology has not yet gained FDA approval. This latest head-to-head comparison included data from more than 1,000 TAVR patients.

Deepak L. Bhatt, MD, MPH, MBA, Director of Mount Sinai Fuster Heart Hospital and the Dr. Valentin Fuster Professor of Cardiovascular Medicine at the Icahn School of Medicine at Mount Sinai, explains what he sees as the top recent trials impacting acute coronary syndrome care (ACS).

Tracking major trends and clinical research in acute coronary syndrome care

Deepak Bhatt, MD, detailed several recent clinical trials that could reshape the way clinicians manage acute coronary syndrome (ACS) patients.

Gudrun Feuchtner, MD, MBA, HCM, assistant professor, cardiovascular imaging, Medical University Innsbruck, Department Radiology, explains how artificial intelligence-based quantitative computed tomography (AI QCT) coronary plaque features are better able to predict risk in women, according the the results of the late-breaking CONFIRM2 study at ACC 2025.

AI-based coronary plaque evaluations highlight elevated heart risks in women

“This is the perfect technique to identify high-risk patients who would benefit from intensive therapies,” imaging specialist Gudrun Feuchtner, MD, told Cardiovascular Business.

Video of Deepak Bhatt explaining the benefits of bentracimab in the late-breaking Phase 3 REVERSE-IT trial.

New drug reverses antiplatelet effects of ticagrelor, helping surgeons avoid a 'bloody mess'

Deepak Bhatt, MD, believes bentracimab could be a game-changer if it gains approval. "I think it's the sort of drug that every emergency room and ICU would have to stock," he said. "A cardiac care unit would have to stock a couple of doses, as would every cath lab."