Novel microscopy method enables high-resolution study of neural brain circuits

Microscopy technique

The technology images neural structures with molecular contrast over millimeter-scale volumes, including mouse pyramidal neurons and their processes (top right). Courtesy of the journal, Science.

A novel imaging technique combining two microscopy methods allowed researchers to visualize neural circuits across the brain at four-times that of typical resolutions, according to research published Jan. 17 in Science. The approach can be completed much faster than previously thought possible.