With the introduction of new molecular imaging modalities, the line between nuclear medicine and radiology blurs a little bit more. While there might have been some tension in the past, with radiologists viewing nuclear medicine as unclear medicine and nuclear medicine physicians operating without the knowledge and experience of cross-sectional imaging, there is now a meeting of the minds of radiologists and nuclear medicine physicians. SPECT/CT utilization is steadily being greeted with more enthusiasm and acceptance within the radiologic community, particularly due to its ability to merge anatomical and functional information, and ultimately, increase diagnostic accuracy and expediency.