Medical Imaging

Physicians utilize medical imaging to see inside the body to diagnose and treat patients. This includes computed tomography (CT), magnetic resonance imaging (MRI), X-ray, ultrasound, fluoroscopy, angiography,  and the nuclear imaging modalities of PET and SPECT. 

Navidea awarded NIH SBIR grant for NAV4694 beta-amyloid imaging agent phase III clinical program aimed at Alzheimer’s disease

Navidea Biopharmaceuticals announces award of a Small Business Innovation Research (SBIR) grant from the National Institute On Aging (NIA) of the National Institutes of Health (NIH) in connection with the Company's Phase 3 clinical program for its NAV4694 beta-amyloid imaging agent as an aid in the differential diagnosis of Alzheimer’s disease.

Navidea Biopharmaceuticals signs manufacturing agreement with Siemens’ PETNET Solutions for NAV4694 beta-amyloid imaging agent

Navidea has signed an agreement with Siemens’ PETNET Solutions that grants PETNET Solutions the right to manufacture Navidea’s Fluorine-18 labeled NAV4694, an investigational beta-amyloid PET imaging agent, which is currently being evaluated in Phase 2 and 3 clinical trials evaluating subjects with signs or symptoms of cognitive impairment such as Mild Cognitive Impairment and Alzheimer’s disease.

Regadenoson stress PET/CT MPI trumps SPECT for CAD detection

Regadenoson stress Rb-82 PET/CT myocardial perfusion imaging (MPI) is highly sensitive, 92 percent, for the detection of obstructive CAD and beats SPECT MPI, according to a study published online Aug. 12 in the Journal of Nuclear Medicine.

Atomic imaging reveals how flame retardants compete with estrogens in the body

Flame retardants mimic estradiols in the body, potentially causing havoc on natural endocrine homeostasis, according to new 3D x-ray crystallography research published online Aug. 19 in Environmental Health Perspectives.

Novel oncologic PET tracer captures cell death

A new facet of cancer imaging targets apoptosis, the process of cell death, to help select and monitor anticancer therapies, according to a study published Aug. 15 in the Journal of Nuclear Medicine.

Quantitative PET required to avoid pitfalls of amyloid imaging over time

Variability in longitudinal standard uptake value ratios when imaging Alzheimer’s patients with C-11 PiB and other amyloid agents create inaccurate portraits of disease progression, warranting a fully quantitative PET protocol for long-term research, according to a study published online Aug 12 in the Journal of Nuclear Medicine.

FDG PET hot spots predict better prognosis in spinal surgery patients

Doctors can now tell how effective a surgery for degenerative cervical myelopathy will be based on how much FDG is taken up by the cervical spinal cord, according to research published online August 5 in the Journal of Nuclear Medicine.

FDG PET keeps tabs on lung oxygenation by quantifying pulmonary blood flow

In cases of acute lung injury, pulmonary blood flow (PBF) provides potentially critical information about lung aeration. An FDG PET method of compartmental modeling may quantify PBF by estimating regional fraction of blood, a breath of fresh air for pulmonary imaging, according to a study published August 1 in the Journal of Nuclear Medicine.