A newly developed software called Datinrad has combed through extensive literature and compiled more than two hundred radiopharmaceutical interactions and adverse effects is now accessible through a single PC portal, according to an article published July 15 in the Journal of Nuclear Medicine Technology.

Standard methods of evaluation for Alzheimer’s disease (AD) including cognitive tests and one-time PET imaging do not provide a bird’s eye view of disease development. A technique combining a range of examinations and a series of F-18 FDG PET studies is providing researchers valuable information about AD formation, according to research published July 12 in the Journal of Nuclear Medicine.

Rather than looking at the global deposition of beta-amyloid in the brain, it may be more valuable to analyze its spatial pattern, now thought to have a stronger association with memory decline, according to a study published July 15 in Neurobiology of Aging.

Amyloid imaging has been the single stitch holding Alzheimer’s imaging together even though beta-amyloid plaque is typically interwoven in the brain with tangles of tau proteins, but that may soon change as two new tau radiotracers tighten the knit of novel dementia imaging, according to a study published July 15 in the Journal of Nuclear Medicine.

C-11 flumazenil (FMZ) PET has been found to have superior localizing specificity compared with F-18 FDG PET for patients with refractory focal epilepsy. However, there are logistical limitations inherent in the use of C-11. A promising potential alternative is F-18 FMZ, according to a study published July 15 in the Journal of Nuclear Medicine.

RadNet Inc. (Nasdaq:RDNT), a national leader in providing high-quality, cost-effective, fixed-site outpatient diagnostic imaging services through a network of 248 subsidiary-owned and/or operated outpatient imaging centers, announced its participation in a clinical trial to evaluate the biomarker effects of the investigational drug E2609, a BACE inhibitor, which is being developed for the potential disease modifying treatment of Alzheimer's disease (AD).

Evaluation of adrenal nodules with F-18 FDG PET/CT was given a mean score of 93 percent diagnostic accuracy with an almost equally high percentage of interreader agreement, suggesting subjective visual interpretation is an effective method of evaluation, according to a review published in the August issue of Academic Radiology.

Adjuvant chemotherapy may not be the best option for patients with certain subtypes of breast cancer who show no clear benefit, according to an extensive retrospective of four clinical trials published June 12 in Breast Cancer Research and Treatment.