Nuclear Medicine

Nuclear medicine (also called molecular imaging) includes positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. Nuclear imaging is achieved by injecting small amounts of radioactive material (radiopharmaceuticals) into patients before or during their scan. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

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Industry partnership set to advance research on theranostics

The deal will create a Therapy Command Center to support the study and use of theranostics across Massachusetts General Hospital and its affiliated centers in bordering states. 

2025 SNMMI Image of the Year

SNMMI unveils its 2025 Image of the Year

The designation was awarded to a research team from China, who analyzed the efficacy of a novel radiotracer developed to target expression of the PD-L1 protein in suspected head and neck cancers. 

3 industry partnerships, 1 clinical aim: Enriching the global supply chain of medical isotopes

Nuclear medicine operations may soon enjoy steadier flows of certain in-demand radioisotopes. If so, much credit will go to companies that had the strategic sense to collaborate with each other. 

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Tau tangles on PET scans may signal impending cognitive decline in asymptomatic individuals

New data highlight the significance of tau-positive imaging in the progression of Alzheimer’s disease. 

Bristol Myers Squibb

Bristol Myers Squibb will pay $350M-plus to add prostate cancer imaging agent

Subsidiary RayzeBio has inked a definitive deal to license the worldwide rights for the drug from Philochem, a Swiss biotechnology firm. 

Imagers reviewing flurpiridaz F-18 (Flyrcado) myocardial perfusion PET images. Image from GE Healthcare

FDA-cleared software increases throughput for flurpiridaz back-to-back rest-stress imaging

The new F-18 flurpiridaz radiotracer is expected to help drive cardiac PET growth, but it requires waiting between rest and stress scans. Software from MultiFunctional Imaging can help care teams combat that problem.

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Radiopharma firm Telix launches new prostate cancer imaging agent Gozellix in US

The PET (positron emission tomography) product is now commercially available through distributors including Cardinal Health, PharmaLogic, Jubilant Radiopharma, and RLS. 

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Startup developing ultracompact PET imaging scanner raises $8.5M

Founded in 2018, Positrigo scored U.S. Food and Drug Administration clearance last year for its NeuroLF brain PET system, which is targeted toward Alzheimer's.