Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Is heart failure hereditary? Researchers say 'maybe'

A new study, published July 11 in the Journal of the American Medical Association, suggests heart failure (HF) may be moderately hereditary.

July 13, 2018

FDA approves less-invasive LVAD implant procedure

The FDA has cleared a less-invasive implant approach for Medtronic’s HeartWare HVAD system, allowing the left ventricular assist device (LVAD) to be placed through a small incision between the ribs. It is the first LVAD approved in the U.S. to be inserted with this technique, according to Medtronic.

July 11, 2018

APOL1 genotypes, CVD not linked in postmenopausal black women

New research published in the Journal of the American Medical Association suggests an association between black postmenopausal women who are carriers of apolipoprotein L1 (APOL1) genotypes and hospitalizations for heart failure with preserved ejection fraction (HFpEF). The findings, however, do not support an association between APOL1 genotypes and coronary heart disease, stroke or mortality.

July 6, 2018
Macaque monkey

Human stem cells reverse heart failure in monkeys

Human stem cells helped restore left ventricular ejection fraction (LVEF) in monkeys induced with experimental heart failure, giving scientists hope a similar treatment could work in humans following myocardial infarction.

July 3, 2018

Tool predicts which patients gain the most from ICDs

The thinking behind the Seattle Proportional Risk Model goes like this: As the annual risk for all-cause mortality increases, the likelihood that the death will be sudden—or something an ICD could prevent—goes down.

June 28, 2018
Baylor St. Luke's Medical Center in Houston

St. Luke’s in Houston to lose Medicare funding for heart transplant program

Just a week after Baylor St. Luke’s Medical Center in Houston reopened its heart transplant program, CMS sent a letter to the hospital saying it will cut off funding for the program beginning Aug. 17.

June 25, 2018

Cardiac resynching unnecessary after LVAD placement, study suggests

Continuing cardiac resynchronization therapy (CRT) appeared to offer no benefit to patients who received a continuous flow left ventricular assist device (CF-LVAD), according to a multicenter study published in the Journal of the American Heart Association.

June 22, 2018
hospital

Differences in hospitals' short-term heart failure mortality persist to 5 years

Heart failure patients treated at hospitals with lower 30-day mortality rates also enjoy a survival benefit one, three and even five years later, suggesting a short-term risk-standardized mortality rate (RSMR) may deserve additional weight in CMS’s financial incentive programs.

June 22, 2018