Vascular & Endovascular

This channel includes news on non-coronary vascular disease and therapies. These include peripheral artery disease (PAD), abdominal and thoracic aortic aneurysm (AAA and TAA), aortic dissection, pulmonary embolism (PE), critical limb ischemia (CLI), carotid artery and stroke interventions, venous interventions, deep vein thrombosis (DVT), and interventional radiology therapies. The focus on most of these therapies is minimally invasive, catheter-based procedures performed in a cath lab.

Genetically modified thrombolytic boosts reperfusion after stroke

Alteplase is sometimes administered to dissolve clots before endovascular thrombectomy in patients with ischemic stroke. But a new study in the New England Journal of Medicine demonstrates tenecteplase, a genetically modified form of alteplase, is associated with better blood flow restoration and improved functional outcomes.

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Novel device treats pulmonary embolism without clot-dissolving drugs

A new device allows clinicians to remove blood clots from the pulmonary arteries and improve right ventricular function without the use of thrombolytics, according to a late-breaking clinical study presented April 26 at SCAI 2018 in San Diego.

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American Airlines sued after passenger dies after in-flight pulmonary embolism

The family of a newlywed nurse is suing American Airlines after she fell ill on a flight and died. The cause of her death was determined to be an acute massive pulmonary embolism and cardiogenic shock.

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Exercise interventions for PAD may require personal support

A randomized trial published April 24 in JAMA suggests patients with lower-extremity peripheral artery disease (PAD) can’t be expected to improve walking performance on their own, even with the aid of wearable activity trackers and telephone coaching sessions.

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Medtronic DCB approved to treat longer lesions

Medtronic’s IN.PACT Admiral drug-coated balloon (DCB) has received an expanded indication from the FDA and is now cleared to treat long superficial femoral artery lesions up to 360 millimeters, the company announced April 23.

Mitochondrial antioxidant may reverse vascular aging

An antioxidant that targets cellular mitochondria appeared to reverse age-related vascular changes by 15 to 20 years in older adults, according to a small, first-in-human study published April 16 in Hypertension.

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Researchers: 'The more you smoke, the more you stroke'

Men under the age of 50 who smoke are more likely to have a stroke—and that risk increases with how much an individual smokes, according to new research published April 19 in Stroke.

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Interfacility transfers for stroke are increasing—maybe too much, researchers say

The odds of stroke patients being transferred from one hospital to another more than doubled from 2006 to 2014. While this is good for patients who may need more advanced care than a small community or rural hospital can provide, it is also important to limit the number of unnecessary transfers, researchers said.