Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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What new valve-in-valve TAVR data tell us about valve durability

Age, diabetes and smoking were all also found to be “significant predictors” of reduced valve durability among SAVR patients.

SAVR a valuable treatment option for asymptomatic patients with severe AS

Early valve replacement was associated with improved outcomes in a new study published in Circulation.

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SAVR associated with 'substantial' survival rates

The procedure is especially effective when treating younger, low-risk patients. 

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Certain patients with chronic kidney disease face a higher risk of death after TAVR

No such trend was reported among patients with end-stage kidney disease.

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Patient frailty not a key factor when choosing between TAVR and SAVR

Frailty measurements may still provide helpful information in other ways, of course. 

What new research tells us about TAVR and platelet-to-lymphocyte ratios

The blood-based biomarker was previously associated with worse acute coronary syndrome outcomes. What does it mean for TAVR patients?

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New risk calculator detects TEER patients who may need to be readmitted for HF

Once the tool's performance is properly validated, it could help clinicians deliver better patient care and result in significant cost savings for health systems.

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How the presence of AFib can impact TAVR, SAVR outcomes

AVR patients may require a longer hospitalization if they present with pre-existing or new-onset AFib.