Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

‘A victory for TAVR’: How treatment impacts elderly patients in their last year of life
New research out of Denmark explored how undergoing TAVR may or may not influence the final year of a patient's life.
Top cardiology video interviews in 2024
A list of the most popular video interviews on Cardiovascular Business in 2024 based on reader analytics.
CMS proposes Medicare coverage for transcatheter tricuspid valve replacement
Edwards Lifesciences sent a formal request to CMS in February after its Evoque TTVR device gained FDA approval. The agency is now accepting public comments for 30 days.
Hydra TAVR valve gains key approval as global reach continues to grow
The self-expanding device is now available in more than 20 countries and received CE mark approval back in 2020. However, it has not yet been approved by the U.S. Food and Drug Administration for use in the United States.
SAVR outperforms TAVR in patients with bicuspid aortic valves
BAV patients are often excluded from TAVR trials, creating uncertainty about the best way to treat that population when aortic valve replacement is required. To learn more, researchers tracked CMS data from 2018 to 2022, presenting their findings in The Annals of Thoracic Surgery.

Raj Makkar, MD, Cedars-Sinai’s vice president of Cardiovascular Innovation and Intervention and the Stephen R. Corday, MD, Chair in Interventional Cardiology, explains the ACC 2023 results on the safety and efficacy of transcatheter edge-to-edge mitral valve repair in degenerative mitral regurgitation (MR) study. It was a review of data is from the STS/ACC TVT Registry that was presented at the American College of Cardiology (ACC) 2023 meeting.

New data on real-world TEER outcomes in patients with degenerative MR

TEER can significantly improve a patient's chances of survival, new findings confirm.

April 25, 2023

The Medtronic CoreValve Evolute on display at ACC 2022. The valve performed better than surgical valved in terms on structural deterioration. #ACC22

Redo TAVR appears feasible for most patients with supra-annular, self-expanding Evolut valves

Researchers evaluated data from more than 200 patients who underwent redo TAVR, noting that women and patients with a higher BMI faced a higher risk of coronary flow compromise.

April 20, 2023

layoffs staff cuts termination workforce

Medtronic laying off undisclosed number of employees to reduce costs

“These decisions are never easy, and we’re taking great care to treat all impacted employees with dignity and respect," the company told Cardiovascular Business in a statement.

April 19, 2023

ACS and revascularization after TAVR: New data on a high-risk scenario

“It is vital to identify patients who are at a high risk for ACS after TAVR for potential treatment beforehand,” according a new analysis published in the American Journal of Cardiology.

April 17, 2023

The LuX-Valve Plus transcatheter tricuspid valve replacement (TTVR) device

Cardiologists make history, perform TTVR with new-look valve for first time in U.S.

The new valve was placed inside the damaged valve via a catheter that is inserted through a small incision in the patient's neck.

April 13, 2023

TAVR vs. SAVR in patients with pure aortic regurgitation: Key insights from a new Cleveland Clinic study

Patients with pure native AR are often excluded from clinical trials comparing TAVR and SAVR, leading to a lack of clarity when it comes to the proper treatment of this population.

April 11, 2023