Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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Hypertension identified as risk factor for aortic valve disease

Sustained elevated blood pressure can increase a patient’s risk for both aortic valve stenosis and aortic regurgitation, according to an analysis of 5.4 million non-CVD patients in the U.K.

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Minimally invasive surgery minus cannulation safe, effective for CHD

Minimally invasive cardiac surgery without peripheral cannulation is both safe and effective for correcting a wide range of congenital heart defects, including mitral valve repair and pulmonary stenosis, according to research published in Heart, Lung and Circulation this week.

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Babies born with CHD likely to have enlarged kidneys

Research out of Australia suggests newborns with congenital heart disease (CHD) are likely to have enlarged kidneys at birth—a finding that could help alert physicians to organ abnormalities before a child is born.

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Early discharge after TAVR reduces readmissions

Early discharge following TAVR is associated with fewer readmissions and similar mortality over the following 30 days compared with a standard discharge strategy, according to a meta-analysis published in JACC: Cardiovascular Interventions.

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Pregnancy safe after arterial switch operation

Mothers or infants experienced no adverse cardiac events during 24 pregnancies completed by women who had undergone an arterial switch operation, according to a single-center, retrospective study published online Sept. 5 in JAMA Cardiology.

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Initial learning curve, annual case volume key in TAVR outcomes

A learning curve of at least 225 procedures is required for hospitals to perform transcatheter aortic valve replacements (TAVRs) with the lowest mortality rates, suggests a study of 16 centers participating in an international registry.

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Hospital discharge with oral antibiotics safe for stable endocarditis

Patients hospitalized with endocarditis can be safely switched from intravenous antibiotics to oral medication about halfway through the course of treatment, according to a randomized trial published in the New England Journal of Medicine.

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Patients with new-onset AFib at greatest risk for complications after TAVR

Cardiac patients who develop new-onset atrial fibrillation (AFib) after transcatheter aortic valve replacement (TAVR) are at a higher risk for complications like stroke, myocardial infarction and death than those whose AFib was established before the procedure, researchers report in the current online issue of JACC: Cardiovascular Interventions.