Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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PCHA, children’s hospitals unite to promote transparency in CV surgical outcomes

Children’s hospitals across the U.S. are backing a national effort by the Pediatric Congenital Heart Association to improve transparency in the reporting of cardiac surgical outcomes.

Public reporting of AVR outcomes linked to decreased access

An increase in public reporting of aortic valve surgery outcomes has been tied to a decrease in AVR access for patients with infective endocarditis—the unintended consequence of a push for greater transparency in healthcare.

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TAVR linked to better long-term health status than SAVR

Patients with severe aortic stenosis who undergo TAVR enjoy a minor but significant sustained health benefit that isn’t mirrored in patients who opt for surgical AVR, according to research reported at TCT 2019 in San Francisco.

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TMVR with MitraClip increases life expectancy—at a cost

An economic analysis of COAPT data suggests edge-to-edge TMVR with the MitraClip device is a more affordable long-term treatment option than guideline-directed medical therapy alone for patients with severe secondary MR—but the steep cost of an index TMVR procedure might eclipse that benefit.

3-year COAPT results bolster MitraClip’s success

Results from the COAPT study continue to roll in, and it was all positive news for the MitraClip team at the TCT conference in San Francisco this month.

FDA greenlights early feasibility study for less-invasive TMVR system

Medtronic announced Sept. 27 that it had received FDA approval to launch an early feasibility study for its Intrepid TMVR system using a minimally invasive transfemoral access approach.

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Failed TAVR more common in women, those with PAD

The incidence of aborted procedures during transcatheter aortic valve replacement is falling, according to work published in JACC: Cardiovascular Interventions, but centers with low institutional TAVR volume still struggle to keep up with bigger hospitals’ success.

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Fluoroquinolone use predicts aortic, mitral regurgitation

People who currently take or have recently taken fluoroquinolones face higher odds of aortic and mitral regurgitation, according to a report out of Canada.