Peripheral Artery Disease

Peripheral artery disease (PAD) involves atherosclerosis mainly in the extremities, especially in the legs and feet that lead to ischemia. Untreated, PAD can progress to critical limb ischemia (CLI), also called chronic limb-threatening ischemia (CLTI), which will lead to foot or leg amputation. The mortality rate for these CLI amputees is 70% within three years. There is currently an epidemic of PAD and CLI in the U.S. The majority of patients are defined by health disparities concentrated in the Black, Latino, Native American populations in both rural and low-income urban areas. A large number of PAD patients have other comorbities, with diabetes being one a primary issue.

Interventional cardiology showing more interest in endovascular procedures
Sahil Parikh, MD, said it was clear at TCT 2025 that the specialty is getting more and more involved with endovascular procedures for stroke, pulmonary embolism and peripheral artery disease.
Shockwave Medical’s IVL catheter for peripheral lesions linked to positive 1-year data
The new findings, presented during a late-breaking presentation, focused on 110 PAD patients treated with Shockwave Medical's Javelin Peripheral IVL Catheter.
FastWave lines up principal investigators for pivotal intravascular lithotripsy trial
"The key question isn't just whether a device works, but whether it makes procedures more efficient and provides physicians with a more predictable tool for treating patients with complex arterial disease," explained co-principal investigator Venita Chandra, MD, clinical professor of surgery at Stanford Health Care.
St. Luke’s cuts PAD amputation rate in half with heart team-led wound transition program
Kimberly Campbell, RN, nurse practitioner, Saint Luke's Cardiovascular Consultants, explains how her health system took a heart team approach toward peripheral artery disease.
Shockwave Medical launches new IVL catheter for challenging lesions in Europe
The balloon-free catheter, which already had a successful launch in the United States, has been associated with positive outcomes and the ability to reach certain lesions more accurately than balloon-based IVL platforms.

Exercise interventions for PAD may require personal support

A randomized trial published April 24 in JAMA suggests patients with lower-extremity peripheral artery disease (PAD) can’t be expected to improve walking performance on their own, even with the aid of wearable activity trackers and telephone coaching sessions.

Peripheral Artery Disease

Interventional cardiology showing more interest in endovascular procedures

Shockwave Medical’s IVL catheter for peripheral lesions linked to positive 1-year data

FastWave lines up principal investigators for pivotal intravascular lithotripsy trial

St. Luke’s cuts PAD amputation rate in half with heart team-led wound transition program

Shockwave Medical launches new IVL catheter for challenging lesions in Europe