Hypertrophic Cardiomyopathy (HCM)

Hypertrophic cardiomyopathy (HCM) causes the walls of the left ventricle to become thicker than normal. This can cause a blockage to blood flow in some patient and is classified as obstructive HCM. This is the most common form of HCM where the septum between the ventricles can reduce the blood flow into the aorta. Nonobstructive HCM is where the heart muscle is thickened but does not block blood flow. The thickened walls stiffen and reduce the amount of blood the heart can pump. HCM is usually caused by an inherited genetic variant (familial hypertrophic cardiomyopathy) and can be detected with genetic testing and diagnosed with medical imaging. It is considered widely underdiagnosed. HCM can lead to heart failure and sudden cardiac arrest. Treatments include drug therapy, septal myectomy and alcohol septal ablation.

Purvi Parwani, MD, director of echocardiography, Loma Linda University Medical Center, explains the trend where heart failure imaging guidelines are driving a rising use of mixed multimodality imaging. #ASE #ASE2023

Multimodality imaging helps cardiologists manage heart failure patients—with an assist from AI

Purvi Parwani, MD, discussed the trend toward multimodality imaging for heart failure management. All modalities have their own weaknesses, she explained. 

Video of Hari Naidu, MD, director of the Hypertrophic Cardiomyopathy Center of Excellence at Westchester Medical Center, explaining the role of alcohol septal ablation and surgical myectomy in the era of mavacamten. #HCM #ASE

Surgery, interventional therapies still the best choice for many HCM patients

"You have to look at each patient and understand their goals," one HCM expert said in a new interview. 

Nicholas Smedira MD discusses spetal myectomy in HCM patients and the need for more detailed protocols for HCM care. #HCM #ASE #ASE2023 #myectomy

A surgeon's perspective on treating hypertrophic cardiomyopathy

Nicholas Smedira, MD, a cardiovascular surgeon with Cleveland Clinic, discusses septal myectomy and the need to improve overall HCM care with new standards and evidence-based guidelines.

Hari Naidu, MD, explains that inconsistent diagnostic imaging and how it is reported has likely led to a major underdiagnosis of HCM. #ASE #ASE2023 #HCM

Why hypertrophic cardiomyopathy may be widely underdiagnosed

One expert believes the lack of standardization for how diagnostic imaging in conducted and reported has led to a major underdiagnosis of HCM.

Matt Martinez, MD, Morristown Medical Center HCM program, explains how hypertrophic cardiomyopathy patient management is changing.

Exercise plays a key part in HCM management

Matthew Martinez, MD, detailed the many ways HCM care management is changing during an exclusive interview at ASE 2023.

Stephen Little, MD, discusses trends in echocardiography at ASE 2023. #ASE23 #ASE2023 What is new in cardiac ultrasound.

Back in the spotlight: Exploring echocardiography's revival

American Society of Echocardiography President Stephen Little, MD, says several trends and technologies are coming together at once, leading to renewed interest in echo.

Ted Abraham, MD, explains ASE efforts to increase HCM education and standardization of care. #HCM #ASE #ASE23 #ASE2023

All eyes are on hypertrophic cardiomyopathy now that a drug treatment is in place

Ted Abraham, MD, explained why HCM has entered the limelight at recent cardiology conferences, including ASE 2023.

Christine Seidman, MD, director of the cardiovascular genetics program, cardiovascular medicine specialist, Brigham & Women’s Hospital, discusses the use of genetics to crack the code of cardiovascular diseases to enable earlier prevention and interventions. She was named the winner of the American Heart Association (AHA) 2022 Research Achievement Award, AHA's highest honor.

VIDEO: Using genetics in cardiology to enable earlier interventions

Christine Seidman, MD, director of the cardiovascular genetics program at Brigham & Women’s Hospital, spoke to us about using genetics to crack the code of cardiovascular disease.