Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography,  RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

With the shortage, which pertains specifically to all formulations and concentrations of GE Healthcare’s Omnipaque (iohexol), expected to last until mid-June, several organizations have eluded that conservation efforts are of critical importance.#contrastshortage #CTcontrast #iodinatedcontrast

Have we been 'overdependent' on iodinated contrast? New paper calls into question prior practices before the shortage

"Ultimately, long-term studies are vital to parse out whether the absence of iodinated contrast media greatly affected patient outcomes or if we have been overdependent on ICM unnecessarily.” 

July 28, 2022

FDA temporarily approves importation of a second foreign-labeled iodinated contrast media

Bracco Diagnostics, Inc has been given the go ahead by the U.S. Food and Drug Administration to temporarily import Iomeron (iomeprol injection) into the U.S. market amid the ongoing iodinated contrast media shortage. 

July 20, 2022
Iodine contrast being loaded into a contrast injector in preparation for a cardiac CT scan at Duly Health and Care in Lisle, Illinois. The contrast shortage is causing some healthcare organizations to postpone exams and procedures and ration contrast supplies. Photo by Dave Fornell

Substituting iodinated contrast media in patients with a history of ICM reactions reduces risk by 61%

“For patients with a prior ICM-induced hypersensitivity reaction, healthcare providers must balance the benefit of ICM reuse against the risk of a repeat reaction,” authors of a new meta-analysis published in Radiology said.

July 20, 2022
contrast shortage

Generic, FDA approved contrast agent set to hit the market in wake of nationwide shortage

On July 18 Fresenius Kabi announced that they are rolling out a line of generic contrast media products, starting immediately with Iodixanol Injection USP. 

July 19, 2022
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Contrast shortage update: FDA opens door for U.S. providers to order foreign-labeled Bayer contrast media

Per Bayer’s communications, the contrast agent is manufactured at the same site in Berlin, Germany as the Ultravist that is intended for U.S. markets, but due to its intended distribution abroad it lacks current FDA-approved labeling. 

July 18, 2022
With the shortage, which pertains specifically to all formulations and concentrations of GE Healthcare’s Omnipaque (iohexol), expected to last until mid-June, several organizations have eluded that conservation efforts are of critical importance.#contrastshortage #CTcontrast #iodinatedcontrast

Contrast shortage update: Supplies could continue to lag until September

GE previously indicated that the iodinated contrast shortage would resolve by the end of June.

July 8, 2022

Measures associated with hospital readmission of pancreatitis patients

Beyond readmission, 32.9% of patients with increased pancreatic necrosis volumes required additional invasive interventions.

July 6, 2022
enlarged parathyroid gland

Routine CT scans offer opportunistic assessments of the parathyroid gland

Such assessments could “decrease existing diagnosis gaps,” according to a new study published in Academic Radiology

June 29, 2022